Top 25 College Hoops Picks Against the Spread – Wednesday, January 15

Published 1:28 am Wednesday, January 15, 2025

There are six games featuring a ranked team on the Wednesday college basketball schedule, including the Kansas Jayhawks versus the Iowa State Cyclones. If you’re seeking against-the-spread picks for each matchup, keep reading.

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AP Top 25 Picks ATS Today

No. 2 Iowa State Cyclones vs. No. 9 Kansas Jayhawks

Spread Prediction

  • Computer Prediction: Iowa State 75, Kansas 71
  • Projected Favorite: Iowa State by 3.5 points
  • Pick ATS: Kansas (+5.5)

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Key Facts

  • Time: 7:00 PM ET
  • Location: Ames, Iowa
  • Venue: James H. Hilton Coliseum
  • TV Channel: ESPN2
  • Live Stream: Watch this game on Fubo (Regional restrictions may apply)

No. 12 Michigan State Spartans vs. Penn State Nittany Lions

Spread Prediction

  • Computer Prediction: Michigan State 81, Penn State 70
  • Projected Favorite: Michigan State by 10.3 points
  • Pick ATS: Penn State (+11.5)

Bet on the Michigan State-Penn State spread—or any other NCAA men’s basketball matchup—with BetMGM!

Key Facts

  • Time: 7:30 PM ET
  • Location: East Lansing, Michigan
  • Venue: Jack Breslin Students Events Center
  • TV Channel: BTN
  • Live Stream: Watch this game on Fubo (Regional restrictions may apply)

No. 6 Tennessee Volunteers vs. No. 23 Georgia Bulldogs

Spread Prediction

  • Computer Prediction: Tennessee 74, Georgia 65
  • Projected Favorite: Tennessee by 9.2 points
  • Pick ATS: Georgia (+11.5)

Bet on the Tennessee-Georgia spread—or any other NCAA men’s basketball matchup—with BetMGM!

Key Facts

  • Time: 8:00 PM ET
  • Location: Knoxville, Tennessee
  • Venue: Thompson-Boling Arena
  • TV Channel: SEC Network
  • Live Stream: Watch this game on Fubo (Regional restrictions may apply)

No. 10 Houston Cougars vs. West Virginia Mountaineers

Spread Prediction

  • Computer Prediction: Houston 74, West Virginia 61
  • Projected Favorite: Houston by 13.0 points
  • Pick ATS: West Virginia (+17.5)

Bet on the Houston-West Virginia spread—or any other NCAA men’s basketball matchup—with BetMGM!

Key Facts

  • Time: 8:00 PM ET
  • Location: Houston, Texas
  • Venue: Fertitta Center
  • TV Channel: ESPN+
  • Live Stream: Watch this game on ESPN+

Washington Huskies vs. No. 17 Purdue Boilermakers

Spread Prediction

  • Computer Prediction: Purdue 77, Washington 69
  • Projected Favorite: Purdue by 8.0 points
  • Pick ATS: Purdue (-7.5)

Bet on the Washington-Purdue spread—or any other NCAA men’s basketball matchup—with BetMGM!

Key Facts

  • Time: 9:30 PM ET
  • Location: Seattle, Washington
  • Venue: Alaska Airlines Arena at Hec Edmundson Pavilion
  • TV Channel: BTN
  • Live Stream: Watch this game on Fubo (Regional restrictions may apply)

UNLV Rebels vs. No. 22 Utah State Aggies

Spread Prediction

  • Computer Prediction: Utah State 77, UNLV 70
  • Projected Favorite: Utah State by 7.0 points
  • Pick ATS: Utah State (-4.5)

Bet on the UNLV-Utah State spread—or any other NCAA men’s basketball matchup—with BetMGM!

Key Facts

  • Time: 11:00 PM ET
  • Location: Las Vegas, Nevada
  • Venue: Thomas & Mack Center
  • TV Channel: CBS Sports Network
  • Live Stream: Watch this game on Fubo (Regional restrictions may apply)

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